关于21三体综合征的知识

jintianjidajiajieshaoyixia21santizonghezheng，yijijieshiyixiahewei21santizonghezheng。

一、21三体综合征病因

 1866nian，dr.john langdon downdiyiciduitangshizonghezhengdedianxingtizhengbaokuozheileihuanerjuyouxiangsidemianbutezhengjinxingwanzhengdemiaoshubingfabiao，yinci，zheiyizonghezhengyiqimingzimingmingweitangshizonghezheng（downzonghezheng）。 1959nianzhengshiletangshizonghezhengshiyouransetiyichangerdaozhide。xiandaiyixuezhengshi，tangshizonghezhengfashenglvyumuqinhuaiyunnianlingyouxiangguan，xi21haoransetideyichang，yousanti、yiweijiqianhesanzhongleixing。gaolingyunfu、luanzilaohuashifashengbufenlidezhongyaoyuanyin。

二、21三体综合征高风险

 21santizonghezhengbushiyichuande，tadefabingwanquansuiji，21santizonghezhenggaofengxianzhiheyunfunianlingyouguan，nianlingyueda，fabinglvyuegao。1/310congshuzhishangkanshidiwei，danhenjiejinlinjiezhi1/270。buguobuyaotaidanxin，tangshishaichazhunquelvzhiyou70%，chachulaigaoweideqishi90%yishangdoushizhengchangde。buguohaishijianyinizuoyangshuichuanciquezhenyixia，tugefangxin。yangshuichuancizhunquelvhengao，jiushiyoudayue0.5%deliuchanfengxian，buguozheishixiaogailvshijianle，yibandoubuhuiyoushenmeshide。suoyiwomenyidingyaozhuzhong21santizonghezhenggaofengxian。

 yangshuichuanciyouyidingdeliuchanfengxian，danzhiyou0.5％-1％，yibanbuhuiduihaizizaochengyingxiangde。ruguonihaishidanxinzheidianxiaofengxian，kecankaoyixiayixiangxinjishu，jiao“wuchuangchanqianjiyinjiancejishu”，zhixuyaozaimuqinshoubeishangchou5mlxue，jiukeyijiancetaiershifouweitangshier，zhunquelvchaoguo99％（yuyangshuichuancixiangdang），qiewurenhefengxian。

三、21三体综合征正常值是多少

 21santizonghezhengzhengchangzhishiduoshaoni？zhengchangqingkuangxia，renyou46ge23duiranseti，21、18、13santijiushitaierdedi21dui、di18dui、di13duiransetibizhengchangde2ge，duochulai1ge，jiujiaoxxsanti。qizhong21santijiushitangshizonghezheng。 renhenianlingdeyunfudouyoukenenghuaishangransetiyichangdetaier，danshiransetiyichangdefashenglvsuizheyunfunianlingdezengzhangermingxianzengjia，ru25suiyixiadeyunfuzhongransetiyichangdefashengjilvwei1：1185，er25suishizegaoda1：335，gu25suiyishangdegaolingyunfuxuzuoransetijiancha。 1、tangshishaichaweikenengxingjiancha：gaoweirenqunzhishishuotaiergengyoukenengshitangshier，diweirenqunzhongyeyoukenengshitangshier 2、zaiquanbuyunfuzhongyueyou1/10deyunfushaichashigaoweirenqun，gaoweirenqunzhong1~2/100shitangshier，yejiushizaiyunfuzhongyou1~2/1000shitangshier 3、dangyanxueshaichazhidayu1/270weigaoweirenqun，zhengchangzhishi1/700zuoyou。guojishangbiaozhunshi1/270 4、tangshishaichazhishixiuzhengzhi。yingxiangtangshishaichazhideyinsuzhuyaoyou：yunfunianling，yunzhou，taierfenmidetaijiadanbai，taipanfenmiderenrongjisu，yaowuyinsu，yichuanyinsudeng。baotaishichi“duolima”shirenrongjisuchaochu21santizonghezhengzhengchangzhikenengyingxiangtangshishaichazhi。